Devastate features a 2D anime art style and focuses on interactive character development. Players can interact with a mysterious, beautiful girl lying in a laboratory bed, learning her story through dialogue and offering companionship and care. Devastate offers items such as stun guns, buckets, and stimulants, each with different functions. A variety of exquisite outfits are also available for customization, allowing players to create adorable looks, strengthen their bond, and help her regain her smile and vitality.